Clinical evidence began to ______ suggesting that the new drugs had a wider range of useful effect than had been predicted from experiments in animals.

The plan has to be ________ to meet the real situation.

To keep healthy, most retired old people____ jogging as a regular form of exercise.

Last month in the US Open final in New York, the Scot won again and         his first Grand Slam win．

 The engine _______ smoke and steam.