You will _______ your health if you work so hard，eat a little food and sleep badly．

It _______to John that he had left the door unlocked.

—How old is Ms Jessica?—Don’t ask her how old she is—she’s really ______ about it.

 After marriage, the world-famous man, who was a leading role in physics, decided to give up his wife ________ his career（事业）.

He had tried everything but it made little ____.