—Did you look up the time of trains to Shanghai? —Yes, the earliest train is _____ to leave at 5:30 am.

______seems to be no possibility that the student majoring in liberal-arts can win the first prize in the100-meter race.

       asleep        a knock at the door awakened her．

The boy is very brave. I         he         the tall tree.

When ______ comes to research into heart disease and its effects on the body, we do not have adequate substitutes for the use of animals.